Opioid substitution therapy as a strategy to reduce deaths in prison: retrospective cohort study
نویسندگان
چکیده
OBJECTIVES To describe deaths in prison among opioid-dependent people, and examine associations between receipt of opioid substitution therapy (OST) and risk of death in prison. DESIGN Retrospective cohort study. SETTING Adult prisons in New South Wales (NSW), Australia. PARTICIPANTS 16 715 opioid-dependent people who were received to prison between 2000 and 2012. INTERVENTIONS Opioid substitution therapy. PRIMARY OUTCOME MEASURES Natural and unnatural (suicide, drug-induced, violent and other injury) deaths in prison. RESULTS Cohort members were in prison for 30 998 person-years (PY), during which time there were 51 deaths. The all-cause crude mortality rate (CMR) in prison was 1.6/1000 PY (95% CI 1.2 to 2.2/1000 PY), and the unnatural death CMR was 1.1/1000 PY (95% CI 0.8 to 1.6/1000 PY). Compared to time out of OST, the hazard of all-cause death was 74% lower while in OST (adjusted HR (AHR): 0.26; 95% CI 0.13 to 0.50), and the hazard of unnatural death was 87% lower while in OST (AHR: 0.13; 95% CI 0.05 to 0.35). The all-cause and unnatural death CMRs during the first 4 weeks of incarceration were 6.6/1000 PY (95% CI 3.8 to 10.6/1000 PY) and 5.5/1000 PY (95% CI 2.9 to 9.4/1000 PY), respectively. Compared to periods not in OST, the hazard of all-cause death during the first 4 weeks of incarceration was 94% lower while in OST (AHR: 0.06; 95% CI 0.01 to 0.48), and the hazard of unnatural death was 93% lower while in OST (AHR: 0.07; 95% CI 0.01 to 0.53). CONCLUSIONS Mortality of opioid-dependent prisoners was significantly lower while in receipt of OST.
منابع مشابه
The impact of opioid substitution therapy on mortality post-release from prison: retrospective data linkage study.
AIMS Release from prison is a high-risk period for mortality. We examined the impact of opioid substitution therapy (OST), for opioid dependence during and after incarceration, upon mortality post-release. DESIGN A cohort was formed of all opioid-dependent people who entered OST between 1985 and 2010 and who, following first OST entry, were released from prison at least once between 2000 and ...
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